John Hunter's MSK Teaching File
Welcome to my Manila site!

FAQ

Feedback

Conference

Case 54 Discussion

Primary hyperparathyroidism with Brown tumor.

Differential diagnosis is extensive, but includes expansile metastasis, myeloma, primary tumor, lymphoma, brown tumor, etc.

This entity usually occurs in patients over 50 with a 2:1 female predominance. The etiology is often parathyroid adenoma. It can be secondary to a paraneoplastic syndrome associated with lung carcinoma in which the tumor secretes a parathyroid-like hormone. It may also be seen in association with MEN (multiple endocrine neoplasia) type 1(with pituitary and pancreatic adenomas) and type 2 (with medullary carcinoma of the thyroid and pheochromocytoma). (40.531, 40.5312)

ref: Sartoris. Musculoskeletal Imaging: The Requisites. Mosby, 1996, pp.295-296.

Case 55

General Radiology Cases